Acute rhinosinusitis
Inflammation of the nasal mucosa and paranasal sinuses that follows blockage of their narrow drainage pathways, almost always viral and self-limiting, with antibiotics reserved for the minority who develop true bacterial superinfection or complications.
In a nutshell
Acute rhinosinusitis usually follows a viral upper-respiratory infection and lasts two to three weeks. Use symptom duration and severity to guide antibiotics: most need self-care, prolonged uncomplicated disease may need no or back-up antibiotics, and orbital or intracranial signs need hospital referral.
Classic presentation
Nasal blockage or discharge with facial or dental pain or pressure and reduced smell after a cold; assess the duration, trajectory, systemic illness and eye or neurological signs.
Key points
- Most cases resolve over two to three weeks without antibiotics; symptoms for around 10 days or less should not receive an antibiotic.
- Bacterial disease is more likely when prolonged symptoms, purulent discharge, severe unilateral pain, fever and marked deterioration cluster, but no single feature is diagnostic.
- For prolonged symptoms without improvement, consider a high-dose intranasal corticosteroid for 14 days in adults and children aged 12 years or over.
- A back-up antibiotic is used if symptoms fail to improve within 7 days or worsen rapidly or significantly; reassess rather than automatically repeating treatment.
- Periorbital oedema, a displaced eye, double vision, ophthalmoplegia or reduced vision requires hospital referral.
- Frontal-bone swelling, meningism, severe frontal headache or focal neurological signs suggests intracranial complication and requires hospital referral.
- Topical nasal decongestants should not be used for more than 5 days.
First-line investigation
Clinical assessment alone for uncomplicated disease; arrange hospital assessment and specialist-led imaging when orbital or intracranial complications are suspected.
Management
Identify complications first
- Refer to hospital for severe systemic infection, orbital signs, newly reduced vision, frontal-bone swelling, meningism, severe frontal headache or focal neurological signs.1
Use self-care for short uncomplicated illness
Consider a nasal corticosteroid for prolonged symptoms
Use no, back-up or immediate antibiotics appropriately
Exam traps
- Antibiotics are not first-line for most acute rhinosinusitis, since the great majority is viral and self-limiting.
- A 'double-sickening' pattern raises the likelihood of bacterial disease but does not replace assessment for severe illness or complications.
- Periorbital swelling or eye signs require hospital referral, not simply escalation of oral antibiotics in the community.
- High-dose intranasal corticosteroid treatment is a consideration for prolonged symptoms in people aged 12 years or over, not routine treatment from day one.
Illustrations
Key sources
- NICE NG79: Sinusitis (acute): antimicrobial prescribing (Current UK recommendations for symptom duration, self-care, nasal corticosteroids, antibiotic strategy, antibiotic choice and hospital referral; page updated with 2026 changes.)
- NICE NG79: Symptoms and signs of acute sinusitis (UK bacterial-likelihood features and symptom-pattern guidance for acute sinusitis.)
- BNF online: analgesics, nasal corticosteroids, decongestants and antibacterials (Current UK prescribing, contraindication, interaction and dose cross-check; use the live monographs and NICE antimicrobial tables before prescribing.)
- NICE NG79: Update information (May 2026 update noting that topical nasal decongestants should not be used for more than 5 days.)
This page is exam revision material, not medical advice, and must not be used for patient care. Always check drug doses against the BNF and current guidance. Full disclaimer.

