UKMLA AKT · Finals · PLAB 1Pass your medical school finals from first principles
A knowledge base and a single-best-answer question bank for the MLA AKT, built against the GMC's content map and scheduled around how memory actually works.
Free to start. Full access £24.99/year · See what’s included
See exactly what's covered · Sitting PLAB 1? It's set against the same map
Understand the mechanism, then prove it in the exam format
Every condition is taught from first principles, so the clinical picture, investigations and management follow from the biology instead of a list to memorise. Here is a real page, and a question that tests it.
Acute coronary syndrome
Rupture of an unstable atherosclerotic plaque triggers thrombus formation that partially or completely occludes a coronary artery, and the resulting ECG and troponin pattern (STEMI, NSTEMI, or unstable angina) dictates exactly how urgently the vessel must be reopened.
One process, a spectrum of severity
Acute coronary syndrome begins when an atherosclerotic plaque's fibrous cap ruptures, exposing thrombogenic material to flowing blood. If the thrombus is non-occlusive, ischaemia occurs without myocyte death (unstable angina). If it partially occludes the vessel, the oxygen-hungry subendocardium infarcts (NSTEMI). If it completely occludes the vessel, the full thickness of the wall infarcts (STEMI). One mechanism produces a graded spectrum of severity.
Why the complications follow from the damage
Complications map directly onto what infarcted: electrically irritable tissue causes arrhythmia, extensive loss of contractile mass causes cardiogenic shock, and damage to a specific structure causes a specific mechanical failure. The posteromedial papillary muscle has a single blood supply, so an inferior infarct can rupture it and cause acute mitral regurgitation, which is exactly what the question on the right is testing.
A 72-year-old woman is on the coronary care unit 4 days after an inferior ST-elevation myocardial infarction treated with primary PCI. She suddenly becomes acutely breathless. On examination there are coarse crackles to both mid-zones and a new loud pansystolic murmur heard best at the apex and radiating to the axilla. Her observations are shown. What is the most likely complication?
| Heart rate | 118beats/min | ↑ | (60–100) |
| Blood pressure | 84/52mmHg | ↓ | |
| Oxygen saturation | 88% | ↓ | (94–98) |
Four things, done properly
First-principles knowledge base
Each condition starts from mechanism, not memorisation - why the biology produces the clinical picture, then presentation, investigations and management.
AKT-format question bank
5-option single-best-answer questions, the same format the MLA AKT and PLAB 1 use, with a written explanation for every option - including why the four wrong answers are wrong.
Mapped to the GMC's MLA content map
400+ condition pages mapped against the GMC's MLA content map - the syllabus behind the UKMLA AKT and PLAB 1.
See exactly what's coveredForgetting-curve scheduling
An SM-2 spaced-repetition scheduler brings items back right before you're likely to forget them, mixing due reviews with new material each session.
Sitting the MSRA? The knowledge base covers its clinical topics, and SJT practice in both official formats is included.
Simple pricing
Start free. Upgrade only if you want the full question bank and SJT practice.
Free
A curated sample of the knowledge base, in full.
Full access
Everything in Free, plus the full textbook and practice bank.