Eyes & VisionPending review

Anterior uveitis

Inflammation of the iris and ciliary body causes a painful, photophobic red eye with an irregular pupil and visual blurring, reflecting immune-mediated attack on the anterior uvea and often signalling an underlying systemic disease.

First principles

The disease is immune-mediated inflammation of the iris and ciliary body

Anterior uveitis is inflammation of the iris (iritis) and/or ciliary body (cyclitis), most often triggered by an autoimmune or HLA-B27-associated process, less commonly by infection. Inflammatory cells and protein leak into the aqueous humour, producing 'cells and flare' visible at the slit lamp. This is a deeper structure than the conjunctiva, which is why the disease behaves so differently: it is painful, sight-threatening, and does not simply settle with lubricants.

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Educational content pending clinical review. Not medical advice.