Renal & Urology

Hypernatraemia

Hypernatraemia is usually a deficit of water relative to sodium; assess volume status and urine concentration, restore circulation first if shocked, then replace water in a controlled specialist-led plan.

Definition

Hypernatraemia is serum sodium above 145 mmol/L, usually reflecting a deficit of water relative to sodium and therefore increased plasma osmolality.

First principles

This is usually a water-access or water-loss problem

A serum sodium above 145 mmol/L represents excess sodium relative to body water. Common drivers are impaired thirst or access to water, gastrointestinal or insensible losses, osmotic diuresis and diabetes insipidus; true sodium gain is less common. Frail, dependent, confused, sedated and very young patients are particularly vulnerable.

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