Allergy & Immunology

A rapidly developing systemic hypersensitivity reaction in which mast-cell mediator release obstructs the airway, closes the small airways and empties the circulation, reversed by intramuscular adrenaline given within minutes.

A reproducible immune-mediated reaction to a specific food, ranging from immediate IgE-mediated urticaria or anaphylaxis to delayed non-IgE-mediated skin and gastrointestinal disease; it is distinct from non-immune food intolerance.