Mastitis and Breast Abscess
Mastitis is breast inflammation on a spectrum from lactational inflammation to bacterial infection; a breast abscess is a drainable collection that needs urgent ultrasound assessment and drainage, while persistent or non-lactational inflammation needs a clear malignancy safety-net.
In a nutshell
Mastitis is breast inflammation, usually lactational, but it is not automatically bacterial. Continue responsive breastfeeding when possible, avoid over-emptying or firm massage, use cold measures and analgesia, and review quickly if not improving. Treat likely bacterial infection using current NICE CKS and BNF/local-formulary advice. A suspected abscess needs urgent ultrasound and drainage. Non-lactational, recurrent or persistent disease needs breast-team assessment to exclude malignancy.
Classic presentation
A breastfeeding patient develops rapid unilateral breast pain, warmth, swelling and a tender wedge or hard area, with or without fever and flu-like symptoms. A persistent focal lump suggests an abscess.
Key points
- Mastitis is an inflammatory spectrum; a hot, red breast does not by itself prove bacterial infection.
- Continue breastfeeding responsively if possible; hand express only enough for feeding or comfort and avoid unnecessary extra pumping.
- Use cold compresses, rest and suitable analgesia; avoid firm massage and tight clothing.
- Review if symptoms are not improving within 12 to 24 hours of appropriate home care or within 48 hours of antibiotics.
- Use current NICE CKS and BNF/local-formulary advice for antibiotic choice, dose, duration and breastfeeding safety.
- A suspected abscess needs urgent ultrasound and drainage; aspiration may need to be repeated.
- Continue breastfeeding during abscess treatment when possible; it does not usually harm the baby.
- Non-lactational, recurrent or persistent inflammation needs breast assessment, not indefinite repeat antibiotics.
First-line investigation
Clinical assessment, with urgent breast ultrasound for a suspected abscess, persistent focal lump or unexpectedly poor response.
Management
Triage severity and abscess risk
Support inflammation and protect feeding
- Continue responsive breastfeeding when possible, hand express only enough for feeding or comfort, check attachment, use cold compresses and suitable analgesia, and avoid firm massage, tight clothing and unnecessary extra expression.2,3,4
- If bacterial infection is likely or symptoms fail to improve with supportive care, use the current NICE CKS and BNF/local formulary for antimicrobial choice, dosing, duration and allergy or breastfeeding checks.1,4,2
Review response promptly
Drain a confirmed abscess
Safety-net atypical and recurrent disease
Exam traps
- Mastitis is not always bacterial, so do not prescribe antibiotics for every red breast without assessing the clinical course.
- Do not advise aggressive breast massage or pumping to empty the breast.
- Do not treat a confirmed abscess with antibiotics alone; arrange drainage and send aspirate for culture.
- Breastfeeding can usually continue during mastitis and abscess treatment.
- Persistent, recurrent or non-lactational mastitis needs breast assessment to exclude inflammatory breast cancer or another lesion.
Illustrations
Key sources
- NICE Clinical Knowledge Summary: Mastitis and breast abscess (NICE CKS professional topic covering lactational and non-lactational mastitis, antimicrobial treatment, abscess assessment and referral; accessed 4 August 2026. Professional access may be restricted.)
- NHS: Mastitis (NHS advice on symptoms, continuing breastfeeding, cold compresses, avoiding unnecessary expression and review if symptoms do not improve; page last reviewed 17 March 2023 and accessed 4 August 2026.)Updated 17 Mar 2023
- NHS: Common breastfeeding problems (NHS breastfeeding support information, including practical feeding and expression advice; accessed 4 August 2026.)
- British National Formulary (BNF) (BNF online prescribing, antimicrobial, analgesic and breastfeeding-safety information; accessed 4 August 2026.)
- NHS: Breast abscess (NHS advice on urgent assessment, ultrasound, needle or incision drainage and continuing breastfeeding during treatment; page last reviewed 14 June 2023 and accessed 4 August 2026.)Updated 14 Jun 2023
- NICE NG12: Suspected cancer: recognition and referral (Current NICE breast referral recommendations for unexplained breast lumps and suspicious breast or skin features; accessed 4 August 2026.)Updated 15 Apr 2026
- NICE NG253: Suspected sepsis in people aged 16 or over (NICE recognition, assessment and immediate management of suspected sepsis in adults; accessed 4 August 2026.)Updated 19 Nov 2025
This page is exam revision material, not medical advice, and must not be used for patient care. Always check drug doses against the BNF and current guidance. Full disclaimer.

