Scarlet Fever
A toxin-mediated group A streptococcal infection causing fever, sore throat, a fine sandpaper rash and strawberry tongue, treated with antibiotics and public-health exclusion.
In a nutshell
Scarlet fever is toxin-mediated group A streptococcal infection: fever and sore throat followed by a fine sandpaper rash, circumoral pallor and strawberry tongue. It is treated with an appropriate current antibiotic, is notifiable in England and requires exclusion for at least 24 hours after the first dose.
Classic presentation
A child with fever and sore throat, flushed cheeks with circumoral pallor, a sandpaper-textured rash and strawberry tongue.
Key points
- Group A streptococcal exotoxin produces the rash.
- The rash may be harder to see on darker skin; texture and palpation still matter.
- Look for strawberry tongue, circumoral pallor and accentuation in skin folds.
- Treat with the current NICE/BNF antibiotic regimen; do not rely on memorised historic doses.
- Exclude from school or nursery for at least 24 hours after the first antibiotic dose.
- Notify suspected cases in England.
- Watch for invasive GAS, deep-neck infection, pneumonia and later post-streptococcal renal or cardiac complications.
First-line investigation
Clinical diagnosis; use throat testing when uncertainty, atypical disease or public-health circumstances make confirmation useful.
Management
Recognise and treat the streptococcal illness
Notify and exclude
Relieve symptoms and safety-net
Manage severe disease and outbreaks
Exam traps
- Scarlet fever is bacterial and needs antibiotics; the other common exanthems in this group are viral.
- Do not dismiss a sandpaper rash because erythema is subtle on darker skin.
- The return-to-school rule is at least 24 hours after the first antibiotic dose, not immediately after starting treatment.
- Quinsy, deep-neck infection, airway compromise and invasive GAS require escalation, not routine primary-care follow-up.
- New illness weeks later with joint, cardiac, renal or systemic features may be a post-streptococcal complication.
Illustrations
Key sources
- UKHSA: Scarlet fever, symptoms, diagnosis and treatment (UKHSA guidance on symptoms, diagnosis, treatment, exclusion and complications.)Updated 29 Mar 2019
- NHS: Scarlet fever (Current NHS information on presentation, testing, antibiotics, contagious period, exclusion and safety-netting.)
- NICE NG84: Sore throat, acute antimicrobial prescribing (Current NICE guidance relevant to acute streptococcal sore throat, antibiotic prescribing and escalation.)Updated 1 Nov 2025
- BNF online (Current UK prescribing information for antibiotics, antipyretics and allergy-specific alternatives.)
- UKHSA: Notifiable diseases and how to report them (Current England notification requirements; suspected scarlet fever is routine-notifiable.)Updated 19 May 2026
- UKHSA: Scarlet fever outbreaks in schools and nurseries (UKHSA outbreak-management guidance for childcare and school settings.)Updated 3 Apr 2023
This page is exam revision material, not medical advice, and must not be used for patient care. Always check drug doses against the BNF and current guidance. Full disclaimer.

